Reserachers thought that vitamin B may slow Alzheimer's disease because it can lower the levels of homocysteine, an amino acid linked to brain cell damage. A new research published in JAMA has demonstrated that vitamin B supplements made very little difference to the decline of mental functions, contrary to what previous studies have suggested
340 patients with mild to moderate Alzheimer's disease were randomised to receive either a combination of vitamin B supplements or a placebo for 18 months. Researchers found no significant difference in reduction of cognitive ability between the groups and concluded that this is not a useful treatment of Alzheimer's disease.
Source: Aisen PS, Schneider LS, Sano M et al. High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease: A Randomized Controlled Trial. JAMA 2008; 300(15): 1774-1783 ( f/t via Athens)
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