Tuesday, November 27, 2007

Prostate cancer may be missed in obese men

A new study found dcotors may be missing a large number of cancer in obese men because the test for prostate-specific antigen (PSA) is unreliable. It may explain why obese men tend to have more aggressive cancer.

Researchers said doctors must take body weight into account when reading test results for prostate cancer because higher body mass index (BMI) is linked to higher plama volume that can lead to dilution of PSA.

Source: "Obesity-Related Plasma Hemodilution and PSA Concentration Among Men With Prostate Cancer" JAMA. 2007;298(19):2275-2280

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