Tuesday, November 27, 2007

Lung transplants may bring more harm than good to children with CF

According to a new study that looked at lung transplants in children with cystic fibrosis (CF) in US, children rarely benefited from such transplants and there were significant risk of harm associated with the transplant. The lead author said it is important to develop criteria to identify the children who would benefit most from transpalnts.

An editorial in the same issue of the NEJM commented that the report's conclusion was shocking, the transplant rules in the US have chanaged since the study was done and the researchers put together data of children and adult patients who have a different success rate.

Source: "Lung Transplantation and Survival in Children with Cystic Fibrosis". NEJM 2007 357(21): 2143-2152 (abstract only)

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