Mental impairment after chemotherapy are often dismissed as depression and anxiety related to the treatment of cancer, but tests on mice showed a popular chemotherapy drug, 5-fluorouracil (5-FU), affects healthy brain cells long after treatment ends, reported The Telegraph.
Cancer Research UK stressed this drug can offer significant benefits that outweigh the effects which some patients report and more work would be needed before any conclusions could be drawn. The researcher said the knowledge gained from these tests can be used to discover ways of preventing such side effects.
Source: "Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system" Journal of Biology 2008, 7:12 doi:10.1186/jbiol69
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