Researchers carried out a meta-analysis of 38 relevant studies carried out in 5 different countries and involving 2.7 million women to examine the association between NSAID use and breast cancer.
The combining results from all 38 studies show that the use of NSAIDs was associated with a 12% reduction in risk of breast cancer. Analysis of all studies examining aspirin use only found a 13% reduction in the risk while the ibuprofen analysis found a 21% reduction in the risk of breast cancer. The authors conclude that there was an overall decreased risk of breast cancer with NSAID use.
Critics say that the use of aspirin and ibuprofen is not without risk in themselves and warn that long-term use of these painkillers would have serious side effects.
Source: Takkouche B, Regueira-Méndez C, Etminan M. Breast Cancer and Use of Nonsteroidal Anti-inflammatory Drugs: A Meta-analysis. Journal of the National Cancer Institute 2008; Oct 7 [Epub ahead of print]
Showing posts with label non-steroidal anti-inflammatory drugs. Show all posts
Showing posts with label non-steroidal anti-inflammatory drugs. Show all posts
Friday, October 10, 2008
Thursday, May 15, 2008
Aspirin daily reduces breast cancer risk
News sources reported a new study that found women who took aspirin, known as non-steroidal anti-inflammatory drugs (NSAIDs) daily were 16% less likely to develop breast cancer.
Researchers studied the questionnaire responses from a previous study conducted in 2003 and used the answers to relate the use of NSAIDs to the chance of developing breast cancer. They concluded that "breast cancer risk was not significantly associated with NSAID use, but daily aspirin use was associated with a modest reduction in oestrogen-receptor (ER)-positive breast cancer." However they suggested further research is required as other studies have shown conflicting results.
Source: "Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health–AARP Diet and Health Study" Breast Cancer Research 2008, 10:R38doi:10.1186/bcr2089 ( free f/t)
Researchers studied the questionnaire responses from a previous study conducted in 2003 and used the answers to relate the use of NSAIDs to the chance of developing breast cancer. They concluded that "breast cancer risk was not significantly associated with NSAID use, but daily aspirin use was associated with a modest reduction in oestrogen-receptor (ER)-positive breast cancer." However they suggested further research is required as other studies have shown conflicting results.
Source: "Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health–AARP Diet and Health Study" Breast Cancer Research 2008, 10:R38doi:10.1186/bcr2089 ( free f/t)
Friday, March 28, 2008
Cod liver oil can cut arthritis drug use
The Daily Mail reported cod liver oil can cut the daily dose of anti-inflammatory drugs needed to ease the pain of arthritis.
The report is based on a small double-blind randomised controlled trial of 97 people aged 37 - 78 with rheumatoid arthritis for an average of 13 years and taking regular NSAID medication. The participants were randomly assigned to either daily capsules of cod liver oil and fish oil or a placebo over 9 months.
60% of participants completed the study, 39% in the cod liver oil group were able to reduce their NSAID intake by about 30% compared with the placebo group. The researchers concluded that cod liver oil capsules could be used by arthritis sufferers to cut their NASID intake.
The study was funded by a company that sells cod liver oil capsules and other food supplements and was published in the journal Rheumatology.
Source: "Cod liver oil (n-3 fatty acids) as an non-steroidal anti-inflammatory drug sparing agent in rheumatoid arthritis" - Rheumatology, published online on March 24, 2008
The report is based on a small double-blind randomised controlled trial of 97 people aged 37 - 78 with rheumatoid arthritis for an average of 13 years and taking regular NSAID medication. The participants were randomly assigned to either daily capsules of cod liver oil and fish oil or a placebo over 9 months.
60% of participants completed the study, 39% in the cod liver oil group were able to reduce their NSAID intake by about 30% compared with the placebo group. The researchers concluded that cod liver oil capsules could be used by arthritis sufferers to cut their NASID intake.
The study was funded by a company that sells cod liver oil capsules and other food supplements and was published in the journal Rheumatology.
Source: "Cod liver oil (n-3 fatty acids) as an non-steroidal anti-inflammatory drug sparing agent in rheumatoid arthritis" - Rheumatology, published online on March 24, 2008
Wednesday, November 07, 2007
Non-prescription painkillers may reduce risk of Parkinson's Disease
A study of 293 patients with Parkinson's Disease found that regular use of some non-prescription drugs known as NSAIDs reduced the risk of developing the disease. The protection persisted for 2 years after the patients stopped taking the drugs.
However, researchers warned that regular use of high dose aspirin and non-aspirin NSAIDs may cause gastrointestinal bleeding and other risks.
Source: "Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease" Neurology 2007; 69: 1836-1842. (Subscription required for f/t)
However, researchers warned that regular use of high dose aspirin and non-aspirin NSAIDs may cause gastrointestinal bleeding and other risks.
Source: "Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease" Neurology 2007; 69: 1836-1842. (Subscription required for f/t)
Subscribe to:
Posts (Atom)